Perfexis brings clinical-grade at-home diagnostic testing directly into your GLP-1, TRT, HRT, peptide, supplement, and nutrition programs. Fully branded. Physician-ordered. CLIA-certified. The data layer that proves your protocols work — and keeps members engaged, accountable, and buying.
GLP-1 medications like Semaglutide and Tirzepatide work across the entire body — not just appetite and weight. They affect blood sugar regulation, lipid metabolism, liver health, kidney function, inflammation, and nutrient absorption all at once. That makes proper baseline testing and consistent monitoring essential, not optional.
This panel covers every system that GLP-1 therapy touches. Before prescribing, it establishes a complete metabolic baseline — flagging anything that could complicate the prescription and giving both the prescriber and patient a clear starting point. Once on the medication, the same panel tracks whether it's actually working: blood sugar improving, lipids moving in the right direction, inflammation coming down, liver health responding, and nutritional status staying intact.
Patients on GLP-1s often dramatically reduce food intake, creating real risk of protein deficiency, B12 depletion, and muscle loss — problems that don't show up on a scale but show up clearly in this panel. Catching them early is the difference between a successful long-term outcome and a patient who feels worse six months in.
Testosterone Replacement Therapy is one of the most nuanced prescriptions in men's health — because the goal isn't simply raising testosterone, it's optimizing the entire hormonal environment around it. Total testosterone alone tells you almost nothing useful. What matters is how much is bioavailable, what's binding it, what it's converting to, and what effect it's having on the blood and prostate. This panel captures all of it.
Before prescribing, these markers establish whether TRT is actually warranted, what starting dose makes sense, and whether there are any contraindications. A patient with elevated hematocrit before they even start is a very different clinical picture than someone with normal levels — and prescribing without knowing that is a risk no responsible provider should take.
Once therapy begins, this panel becomes the monitoring backbone. TRT raises red blood cell production, meaning hematocrit needs to be watched closely. Estradiol rises as testosterone converts, and keeping that conversion in the right range is what separates patients who feel great from those who don't.
GLP-1 medications like Semaglutide and Tirzepatide work across the entire body — not just appetite and weight. They affect blood sugar regulation, lipid metabolism, liver health, kidney function, inflammation, and nutrient absorption all at once. That makes proper baseline testing and consistent monitoring essential, not optional.
This panel covers every system that GLP-1 therapy touches. Before prescribing, it establishes a complete metabolic baseline — flagging anything that could complicate the prescription and giving both the prescriber and patient a clear starting point. Once on the medication, the same panel tracks whether it's actually working: blood sugar improving, lipids moving in the right direction, inflammation coming down, liver health responding, and nutritional status staying intact.
Patients on GLP-1s often dramatically reduce food intake, creating real risk of protein deficiency, B12 depletion, and muscle loss — problems that don't show up on a scale but show up clearly in this panel. Catching them early is the difference between a successful long-term outcome and a patient who feels worse six months in.
Testosterone Replacement Therapy is one of the most nuanced prescriptions in men's health — because the goal isn't simply raising testosterone, it's optimizing the entire hormonal environment around it. Total testosterone alone tells you almost nothing useful. What matters is how much is bioavailable, what's binding it, what it's converting to, and what effect it's having on the blood and prostate. This panel captures all of it.
Before prescribing, these markers establish whether TRT is actually warranted, what starting dose makes sense, and whether there are any contraindications. A patient with elevated hematocrit before they even start is a very different clinical picture than someone with normal levels — and prescribing without knowing that is a risk no responsible provider should take.
Once therapy begins, this panel becomes the monitoring backbone. TRT raises red blood cell production, meaning hematocrit needs to be watched closely. Estradiol rises as testosterone converts, and keeping that conversion in the right range is what separates patients who feel great from those who don't.
GLP-1 medications like Semaglutide and Tirzepatide work across the entire body — not just appetite and weight. They affect blood sugar regulation, lipid metabolism, liver health, kidney function, inflammation, and nutrient absorption all at once. That makes proper baseline testing and consistent monitoring essential, not optional.
This panel covers every system that GLP-1 therapy touches. Before prescribing, it establishes a complete metabolic baseline — flagging anything that could complicate the prescription and giving both the prescriber and patient a clear starting point. Once on the medication, the same panel tracks whether it's actually working: blood sugar improving, lipids moving in the right direction, inflammation coming down, liver health responding, and nutritional status staying intact.
Patients on GLP-1s often dramatically reduce food intake, creating real risk of protein deficiency, B12 depletion, and muscle loss — problems that don't show up on a scale but show up clearly in this panel. Catching them early is the difference between a successful long-term outcome and a patient who feels worse six months in.
Testosterone Replacement Therapy is one of the most nuanced prescriptions in men's health — because the goal isn't simply raising testosterone, it's optimizing the entire hormonal environment around it. Total testosterone alone tells you almost nothing useful. What matters is how much is bioavailable, what's binding it, what it's converting to, and what effect it's having on the blood and prostate. This panel captures all of it.
Before prescribing, these markers establish whether TRT is actually warranted, what starting dose makes sense, and whether there are any contraindications. A patient with elevated hematocrit before they even start is a very different clinical picture than someone with normal levels — and prescribing without knowing that is a risk no responsible provider should take.
Once therapy begins, this panel becomes the monitoring backbone. TRT raises red blood cell production, meaning hematocrit needs to be watched closely. Estradiol rises as testosterone converts, and keeping that conversion in the right range is what separates patients who feel great from those who don't.
This panel was built for the way people actually use these therapies — not in isolation, but together. The patient on GLP-1 who is also running a peptide protocol. The TRT patient who added BPC-157 for recovery. These are not separate clinical pictures. They are one person with one body, and this panel treats them that way.
Most optimization protocols touch the same core systems — metabolism, hormones, inflammation, organ function, and nutrient status. GLP-1s drive metabolic improvement but create nutritional depletion risk. TRT shifts the hormonal environment in ways that ripple across lipids, red blood cells, and liver function. Peptides influence inflammation, tissue repair, and growth signaling depending on the protocol.
hsCRP ties everything together — every one of these therapies has an anti-inflammatory effect as part of its value proposition, and tracking it month over month gives patients and providers a single number that reflects whether the cumulative protocol is moving the body in the right direction at the cellular level. One comprehensive picture. Every system covered.
This expanded panel gives the full hormonal picture required for responsible TRT management. LH and FSH reveal whether the HPG axis is still functioning — critical for understanding natural production suppression and making informed decisions about fertility preservation and HCG co-administration. Prolactin rules out pituitary involvement as a contributing cause of low testosterone. Hemoglobin alongside hematocrit provides a complete red blood cell picture rather than a single datapoint.
This is the panel for new patients, for anyone with a complex hormonal history, and for periodic comprehensive reviews on established protocols. Every marker here has a direct clinical implication — none are included without purpose.
Blood testing tells you where you are. Genetic testing tells you why you got there — and what your body is built to respond to. Together they form a complete picture that neither can provide alone.
For anyone serious about optimization — whether that means TRT, peptides, GLP-1 therapy, or longevity protocols — genetic data transforms every decision from educated guessing into precision. This panel identifies how your body processes carbohydrates and fats at a genetic level, how your muscles respond to training, what vitamin forms you actually absorb, and where your injury and recovery risks lie.
For someone already tracking their labs monthly, knowing that their genes indicate high carbohydrate sensitivity or impaired B12 absorption turns a data point into a directive. The action plan stops being generic — it's built around what their specific biology can actually use. Test once. Inform every recommendation, forever.